Salmeterolisalong-actingβ2-adrenergicreceptoragoNISTthatisclinicallyusedtotreatasthmaandchronicobstructivepulmonarydisease(COPD).Salmeterolexhibitsanti-asthma,anti-fibrotic,andanti-inflammatoryactivities.Invitro,salmeteroldecreasesTGF-β-induceddepositionofcollagenandfibronectin.
| CasNo. | 89365-50-4 |
|---|---|
| Purity | ≥98% |
| Formula | C25H37NO4 |
| FormulaWt. | 415.57 |
| IUPACName | 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | S0245MSDSPDF |
|---|---|
| InfoSheet | S0245InfoSheetPDF |
LambersC,QiY,EleniP,etal.Extracellularmatrixcompositionismodifiedbyβ2-agoniststhroughcAMPinCOPD.BiochemPharmacol.2014Oct1;91(3):400-8.PMID:25107701.
ColemanRA.Onthemechanismofthepersistentactionofsalmeterol:whatisthecurrentposition?BrJPharmacol.2009Sep;158(1):180-2.PMID:19719780.
