Kassininisatachykininneuropeptideoriginallyfoundinamphibianskin;itbindsneurokinin2(NK2)receptorsanddisplaysgastrointestinalmotilitymodulatingactivity.Kassininstimulatesiontransportacrossskinmembranes.Kassininalsoinducescontractionsinbladdermuscleandinhibitsbothgastricacidsecretionandgastricemptying.
| CasNo. | 63968-82-1 |
|---|---|
| Purity | ≥95% |
| Formula | C59H95N15O18S |
| FormulaWt. | 1334.6 |
| ChemicalName | L-alpha-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-alpha-aspartyl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-Methioninamide |
| IUPACName | 3-amino-4-[[1-[2-[[6-amino-1-[[1-[[1-[[5-amino-1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoicacid |
| Synonym | |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | K0172InfoSheetPDF |
|---|
LippeC,BellantuonoV,ArdizzoneC,etal.EledoisinandKassinin,butnotEnterokassinin,stimulateiontransportinfrogskin.Peptides.2004Nov;25(11):1971-5.PMID:15501529.
BolleP,SeveriniC,Falconieri-ErspamerG,etal.Effectsofnaturaltachykininsonporcinelowerurinarytractsmoothmuscle.JAutonPharmacol.2000Jun;20(3):157-61.PMID:11193004.
ImprotaG,BroccardoM.Tachykinins:effectsongastricsecretionandemptyinginrats.PharmacolRes.1990Sep-Oct;22(5):605-10.PMID:2177557.
