L-Phenylalaninol is a non-essential amino acid that exhibits anticancer and antacid activities. In melanoma cells, L-phenylalaninol increases activity of cytochrome c reductase and tau-glutamyl transpeptidase, inhibiting cell proliferation. L-Phenylalaninol also inhibits intestinal absorption of phenylalanine and may decrease gastric acid secretion and ulcer formation.
| Cas No. | 3182-95-4 |
|---|---|
| Purity | ≥98% |
| Formula | C9H13NO |
| Formula Wt. | 151.21 |
| Chemical Name | (S)-2-Amino-3-phenyl-1-propanol |
| IUPAC Name | (2S)-2-amino-3-phenylpropan-1-ol |
| Synonym | S-Phenylalaninol; β-amino-(S)-(9CI)Benzenepropanol |
| Melting Point | 90-93°C |
| Solubility | Soluble in water and methanol. |
| Appearance | Gray or slightly yellow powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | P2919 Info Sheet PDF |
|---|
Landau O, Wasserman L, Deutsch AA, et al.Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846.
Hashizume H, Miyamae T, Morikawa T, et al. Effects of phenylalaninol on centrally induced gastric acid secretion. Chem Pharm Bull (Tokyo). 1992 Nov;40(11):3113-4. PMID: 1477931.
Shimomura K, Fukushima T, Danno T, et al. Inhibition of intestinal absorption of phenylalanine by phenylalaninol. J Biochem. 1975 Aug;78(2):269-75. PMID: 1228171.
