M40isapeptideantagoNISTatgalaninreceptorsthatexhibitsanorexigenicandanxiolyticactivities.Invivo,M40decreasesfoodintake,ethanolconsumption,andreproductivebehavior.M40alsodecreasesstress-inducedanxietyresponsesintheelevatedplusmazeandsocialinteractiontasksandsuppressesdefensiveburyingbehaviorinanimalmodelsofanxiety.
| CasNo. | 143896-17-7 |
|---|---|
| Purity | ≥95% |
| Formula | C94H145N23O24 |
| FormulaWt. | 1981.34 |
| Synonym | 64:PN:US20050009742PAGE:20claimedsequence |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | M0040InfoSheetPDF |
|---|
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KoeglerFH,YorkDA,BrayGA.TheeffectsonfeedingofgalaninandM40wheninjectedintothenucleusofthesolitarytract,thelateralparabrachialnucleus,andthethirdventricle.PhysiolBehav.1999Aug;67(2):259-67.PMID:10477058.
ParkJJ,BaumMJ.IntracerebroventricularinfusionofthegalaninantagonistM40attenuatesheterosexualpartnerpreferenceinferrets.BehavNeurosci.1999Apr;113(2):391-400.PMID:10357463.
