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当前位置: 首页 > 产品中心 > clinical_research > LKT/MIRTAZAPINE/M3368/250 mg
商品详细LKT/MIRTAZAPINE/M3368/250 mg
LKT/MIRTAZAPINE/M3368/250 mg
LKT/MIRTAZAPINE/M3368/250 mg
商品编号: M3368-250mg
品牌: lktlabs
市场价: ¥23980.00
美元价: 14388.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Mirtazapineisapiperazineantidepressantthatalsodisplaysanxiolytic,hypnotic,antiemetic,andorexigenicactivity.MirtazapineactsasanantagoNISTat5-HT2/3receptors,anindirectagonistat5-HT1receptors,andanantagonistatα2-adrenergicreceptors,enhancingNEand5-HTneurotransmission.Thesleep-inducinghypnoticeffectsaremediatedthroughmirtazapine’sinverseagonismathistamineH1receptors,althoughtolerancetothiseffectdevelopsduringchronicuse.Clinically,mirtazapineimprovesthewithdrawalsymptomprofileandaidsinpreventingrelapseinrecentlyabstinentsubstanceabusersinamannersimilarlytootherantidepressants.Thiscompoundalsoshowsefficacyintreatingbehavioralcomplicationsassociatedwithautismspectrumdisorderandpervasivedevelopmentaldisorder.

ProductInfo

CasNo.

61337-67-5

Purity

≥98%

Formula

C17H19N3

FormulaWt.

265.35

ChemicalName

Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine,1,2,3,4,10,14b-hexahydro-2-methyl-

IUPACName

CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

Synonym

Remeron

MeltingPoint

104-108°C

Solubility

SolubleinDMSO(~8mg/mL).

Appearance

WhiteCrystalPowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

M3368MSDSPDF

InfoSheet

M3368InfoSheetPDF

References

KongsakonR,PapadopoulosKI,SaguansirithamR.Mirtazapineinamphetaminedetoxification:aplacebo-controlledpilotstudy.IntClinPsychopharmacol.2005Sep;20(5):253-6.PMID:16096515.

LiappasJ,PaparrigopoulosT,MalitasP,etal.Mirtazapineimprovesalcoholdetoxification.JPsychopharmacol.2004Mar;18(1):88-93.PMID:15107190.

NuttDJ.TolerABIlityandsafetyaspectsofmirtazapine.HumPsychopharmacol.2002Jun;17Suppl1:S37-41.PMID:12404669.

PoseyDJ,GueninKD,KohnAE,etal.Anaturalisticopen-labelstudyofmirtazapineinautisticandotherpervasivedevelopmentaldisorders.JChildAdolescPsychopharmacol.2001Fall;11(3):267-77.PMID:11642476.

AnttilaSA,LeinonenEV.Areviewofthepharmacologicalandclinicalprofileofmirtazapine.CNSDrugRev.2001Fall;7(3):249-64.PMID:11607047.

deBoerTH,MauraG,RaiteriM,etal.NeuRochemicalandautonomicpharmacologicalprofilesofthe6-aza-analogueofmianserin,Org3770anditsenantiomers.Neuropharmacology.1988Apr;27(4):399-408.PMID:3419539.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂