Description
Difloxacin is a fluoroquinolone antibiotic used in veterinary medicine; it’s antibacterial efficacy stems from inhibition of bacterial DNA gyrase. Difloxacin inhibits growth of several types of bacteria, including species of Staphylococcus, Escherichia, and Pasturella.
References
Schink AK, Kadlec K, Hauschild T, et al. Susceptibility of canine and feline bacterial pathogens to pradofloxacin and comparison with other fluoroquinolones approved for companion animals. Vet Microbiol. 2013 Feb 22;162(1):119-26. PMID: 22939523.
Awji EG, Tassew DD, Lee JS, et al. Comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in Staphylococcus pseudintermedius. Vet Dermatol. 2012 Aug;23(4):376-80, e68-9. PMID: 22409306.