Description
DihydroartemisininisasesquiterpenelactonethatcanbederivedfromArtemisia.Dihydroartemisininexhibitsanticancer,antiviral,anti-inflammatory,anti-asthma,andanti-parasiticactivities.Artemisininssuchasdihydroartemisininarebestknownfortheirantimalarialactivity.Dihydroartemisinininducesapoptosisincolorectalcancercells,increasinglevelsofROSandBax;italsoinhibitsmTORC1inrhaBDomyosarcomacells.DihydroartemisinindisplaysantimicrobialactivityagainstPlasmodium,Schistosoma,andhumancytomegalovirus.Thiscompoundalsodecreaseslevelsofinflammatorycells,Th4cytokines,IgE,andmucussecretion,suppressingairwayhyper-responsivenessinanimalmodelsofasthma.
References
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