Enoxacinisafluoroquinoloneantibioticthatisclinicallyusedtotreaturinarytractinfectionsandgonorrhea;likeotherfluoroquinolones,enoxacininhibitsDNAgyraseandtopoisomeraseIV.Enoxacindisplaysantibacterialandanti-resorptiveactivities.Invivo,thiscompounddecreasesRANKL-inducedJNKsignaling,inhibitingosteoclastformation.Additionally,enoxacininhibitsvacuolarH+ATPaseactivity,preventingboneresorption.
| CasNo. | 74011-58-8 |
|---|---|
| Purity | ≥98% |
| Formula | C15H17FN4O3 |
| FormulaWt. | 320.32 |
| ChemicalName | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylicacid |
| IUPACName | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylicacid |
| Synonym | Abenox;Bactidan;Comprecin;Flumark;Penetrex |
| MeltingPoint | 220-224°C |
| Solubility | Insolubleinwater. |
| Appearance | Yellowtooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | E5358InfoSheetPDF |
|---|
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