Ergosterolisasterolcomponentofcellmembranesinyeastandfungi.Ergosterolisatargetformanyantifungalcompounds.Ergosterolexhibitsanti-angiogenic,anticancerchemotherapeutic,andchemopreventiveactivities.Inanimalmodelsofbladdercancer,ergosterolinhibitstumorpromotion.Ergosterolalsoinhibitsneovascularizationanddecreasestumorgrowthinanimalmodelsofsarcoma.
| CasNo. | 57-87-4 | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Purity | ≥96% | ||||||||||||||||||||||
| Formula | C28H44O 396.65 (3β,5α)-Ergostan-3-ol (3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol Ergosterin,ProvitaminD2. 168°C Practicallyinsolubleinwater.Solubleinchloroform,boilingether,boilingalcohol. Whiteoralmostwhitecrystalline 4°C Ambient E6825MSDSPDF E6825InfoSheetPDF RobertsCW,McLeodR,RiceDW,etal.Fattyacidandsterolmetabolism:potentialantimicrobialtargetsinapicomplexanandtrypanosomatidparasiticprotozoa.MolBiochemParasitol.2003Feb;126(2):129-42.PMID:12615312. TakakuT,KimuraY,OkudaH.IsolationofanantitumorcompoundfromAgaricusblazeiMurillanditsmechanismofaction.JNutr.2001May;131(5):1409-13.PMID:11340091. YazawaY,YokotaM,SugiyamaK.AntitumorpromotingeffectofanactivecomponentofPolyporus,ergosterolandrelatedcompoundsonraturinarybladdercarcinogenesisinashort-termtestwithconcanavalinA.BiolPharmBull.2000Nov;23(11):1298-302.PMID:11085355. |
