Ethambutol is an antibiotic that inhibits arabinosyl transferase, preventing arabinogalactin synthesis and bacterial cell wall formation. Ethambutol exhibits antibacterial activity against Mycobacterium and is clinically used to treat tuberculosis.
| Cas No. | 1070-11-7 |
|---|---|
| Purity | ≥98% |
| Formula | C10H24N2O2 • 2HCl |
| Formula Wt. | 277.24 |
| Chemical Name | 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol |
| IUPAC Name | (2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol;dihydrochloride |
| Synonym | (+)-2,2'-(ethylenediimino)di-1-butanol; EMB |
| Melting Point | 199-204°C |
| Solubility | Soluble in water. Sparingly soluble in ethanol. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | E7230 MSDS PDF |
|---|---|
| Info Sheet | E7230 Info Sheet PDF |
Plinke C, Walter K, Aly S, et al. Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo. Antimicrob Agents Chemother. 2011 Jun;55(6):2891-6. PMID: 21444710.
Kahana LM. Ethambutol in tuberculosis. Biomed Pharmacother. 1990;44(1):21-3. PMID: 1369688.
