Fenbendazoleisabenzimidazoleanti-parasitic/anti-helminthicthatisusedinveterinarymedicinetotreatinfectionsofGiardia,Strongyloides,andvariousworms.Fenbendazolebindsfungaltubulin,preventingmicrotubulepolymerizationandinhibitinghyphalgrowthandnucleardivision.
| CasNo. | 43210-67-9 |
|---|---|
| Purity | ≥98% |
| Formula | C15H13N3O2S |
| FormulaWt. | 299.35 |
| ChemicalName | [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamicacidmethylester |
| IUPACName | methylN-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate |
| Synonym | HOE-881v;Panacur;SafeGard |
| MeltingPoint | 233°C(dec) |
| Solubility | Insolubleinwater.Slightlysolubleinmostorganicsolvents.SolubleinDMSO. |
| Appearance | Awhiteoralmostwhitecrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | F1650MSDSPDF |
|---|---|
| InfoSheet | F1650InfoSheetPDF |
KüsterT,StadelmannB,AeschbacherD,etal.ActivitiesoffenbendazoleincomparisonwithalbendazoleagainstEchinococcusmultilocularismetacestodesinvitroandinamurineinfectionmodel.IntJAntimicrobAgents.2014Apr;43(4):335-42.PMID:24646943.
LubegaGW,PrichardRK.Specificinteractionofbenzimidazoleanthelminticswithtubulin:high-affinitybindingandbenzimidazoleresistanceinHaemonchuscontortus.MolBiochemParasitol.1990Jan15;38(2):221-32.PMID:2325707.
PrichardRK.Anthelminticsforcattle.VetClinNorthAmFoodAnimPract.1986Jul;2(2):489-501.PMID:3488116.
