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当前位置: 首页 > 产品中心 > clinical_research > LKT/FENTICONAZOLE NITRATE/F1854/250 mg
商品详细LKT/FENTICONAZOLE NITRATE/F1854/250 mg
LKT/FENTICONAZOLE NITRATE/F1854/250 mg
LKT/FENTICONAZOLE NITRATE/F1854/250 mg
商品编号: F1854-250mg
品牌: lktlabs
市场价: ¥1760.00
美元价: 1056.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Fenticonazole is an imidazole derivative that exhibits antifungal, antibacterial, and anti-parasitic activities. Fenticonazole inhibits secretion of proteinase, potentially through antagonism of glucosamine-6-phosphate synthase; it also damages fungal cytoplasmic membranes and inhibits cytochrome oxidases and peroxidases. Fenticonazole displays antimicrobial activity against a variety of organisms, including species of Candida, Trichomonas, and gram positive bacteria. This compound may inhibit 14-α demethylase.

Product Info

Cas No.

73151-29-8

Purity

≥98%

Formula

C24H20Cl2N2OS • HNO3

Formula Wt.

518.41

IUPAC Name

1-[2-(2,4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole;nitric acid

Melting Point

136°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

Info Sheet

F1854 Info Sheet PDF

References

Veraldi S, Milani R. Topical fenticonazole in dermatology and gynaecology: current role in therapy. Drugs. 2008;68(15):2183-94. PMID: 18840006.

Fernández-Alba J, Valle-Gay A, Dibildox M, et al. Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen. J Chemother. 2004 Apr;16(2):179-86. PMID: 15216954.

Palacín C, Tarragó C, Agut J, et al. In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates. Methods Find Exp Clin Pharmacol. 2001 Mar;23(2):61-4. PMID: 11484411.

Milewski S, Mignini F, Covelli I, et al. Specific inhibition of acid proteinase secretion in Candida albicans by Lys-Nva-FMDP. J Med Vet Mycol. 1994;32(1):1-11. PMID: 8207618.

Graziani G, Cazzulani P. Irritation and toxicity studies with fenticonazole applied topically to the skin and mucous membranes. Arzneimittelforschung. 1981;31(12):2152-4. PMID: 7199317.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂