Description
Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy.
Piperacillin is a β-lactam antibiotic that inhibits bacterial cell wall synthesis. Piperacillin is often paired with a β-lactamase inhibitor such as Tazobactam, improving its antibacterial efficacy.
Cas No. | 59703-84-3 |
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Purity | ≥95% |
Formula | C23H26N5O7SNa |
Formula Wt. | 539.54 |
Chemical Name | [[2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxo-1- piperazinyl)carbonyl]amino]-phenylacetyl]amino]-3,3- dimethyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid, monosodium salt |
IUPAC Name | sodium;(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylateInChI: InChI=1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1 |
Synonym | Pentcillin; Pipracil; CL 227193; Isipen; T-1220. |
Melting Point | 183-185°C (dec) |
Solubility | Soluble in water and alcohols. |
Appearance | White or off-White Powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | P3463 MSDS PDF |
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Info Sheet | P3463 Info Sheet PDF |
Fernández-Canigia L, Litterio M, Legaria MC, et al. First national survey of antibiotic susceptibility of the Bacteroides fragilis group: emerging resistance to carbapenems in Argentina. Antimicrob Agents Chemother. 2012 Mar;56(3):1309-14. PMID: 22232282.
Bonfiglio G, Laksai Y, Franceschini N, et al. In vitro activity of piperacillin/tazobactam against 615 Pseudomonas aeruginosa strains isolated in intensive care units. Chemotherapy. 1998 Sep-Oct;44(5):305-12. PMID: 9732144.
Kadima TA, Weiner JH. Mechanism of suppression of piperacillin resistance in enterobacteria by tazobactam. Antimicrob Agents Chemother. 1997 Oct;41(10):2177-83. PMID: 9333044.