LKT/PODOPHYLLOTOXIN/P5712/50 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/PODOPHYLLOTOXIN/P5712/50 mg

LKT/PODOPHYLLOTOXIN/P5712/50 mg

商品编号： P5712-50mg

品牌： lktlabs

市场价： ¥640.00

美元价： 384.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDP5712

CasNo.518-28-5

Purity≥90%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Podophyllotoxinisanon-alkaloidlignanfoundinspeciesofPodophyllumthatexhibitsanticancerandantiviralactivities.Podophyllotoxindisplaysantimitoticaction,bindingtubulinandinhibitingmitoticspindleformation.DerivativesofthiscompoundinhibittopoisomeraseII.Ingastriccancercells,podophyllotoxininducesG2/Mphasecellcyclearrestandapoptosis,decreasesthemitochondrialmembranepotential,increasescytochromecrelease,andinhibitscellularproliferation.Podophyllotoxinisoccasionallyclinicallyusedtotreathumanpapillomavirus(HPV)infection,asitinhibitsviralreproductionthroughinhibitionofE2proteinactivity.

ProductInfo

CasNo.	518-28-5
Purity	≥90%
Formula	C₂₂H₂₂O₈
FormulaWt.	414.41
ChemicalName	(5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3",4":6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one
IUPACName	(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Synonym	Podofilox;Podophyllinicacidlactone
MeltingPoint	114-118°C:Afterdrying183-184°C
Solubility	Slightlysolubleinwater.
Appearance	Whitecrystalpowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

MSDS	P5712MSDSPDF
InfoSheet	P5712InfoSheetPDF

References

JiCF,JiYB.ApoptosisofhumangastriccancerSGC-7901cellsinducedbypodophyllotoxin.ExpTherMed.2014May;7(5):1317-1322.PMID:24940431.

Ramírez-FortMK,AuSC,JavedSA,etal.Managementofcutaneoushumanpapillomavirusinfection:pharmacotherapies.CurrProblDermatol.2014;45:175-85.PMID:24643186.

LiJ,DaiCX,SunH,etal.Protectiveeffectsandmechanismsofcurcuminonpodophyllotoxintoxicityinvitroandinvivo.ToxicolApplPharmacol.2012Dec1;265(2):190-9.PMID:23088858.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂