LKT/PROTOCATECHUIC ACID ETHYL ESTER/P7060/25 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/PROTOCATECHUIC ACID ETHYL ESTER/P7060/25 g

LKT/PROTOCATECHUIC ACID ETHYL ESTER/P7060/25 g

商品编号： P7060-25g

品牌： lktlabs

市场价： ¥2340.00

美元价： 1404.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDP7060

CasNo.3943-89-3

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Protocatechuicacidisadihydroxyphenolicacidoriginallyfoundincruciferousvegetables,sunflowers,rice,andotherplants.Protocatechuicacidexhibitsawidevarietyofbeneficialproperties,includingantioxidative,anti-inflammatory,anti-parasitic,antibacterial,anti-metastatic,andanticanceractivities.ProtocatechuicacidinhibitsTNF-inducedexpressionandreleaseofadhesionmoleculesandpro-inflammatorycytokinesaswellasADP-inducedexpressionofplateletP-selectin.ThiscompoundincreasesquinonereductaseactivityandactsasarADIcalscavengeraswell.Additionally,protocatechuicacidimprovespathology,motorfunction,andcognitionanddecreasesinfarctsizeinanimalmodelsofbilateralcommoncarotidarteryocclusion.Thiscompoundisactiveagainstbothgrampositiveandgramnegativebacteriaandexertsantiparasiticactivityinvitroandinvivo,indicatingpotentialbenefitasanantimalarialtreatment.Invitro,protocatechuicacidinhibitsRhoBactivation,decreasingexpressionofmatrixmetalloproteinase2(MMP2)andinactivatingNF-κBandalsoinhibitshumantopoisomeraseII;theseactivitiesresultininhibitionofmetastasis,invasion,andproliferationinavarietyofcellularmodels.

ProductInfo

CasNo.	3943-89-3
Purity	≥98%
Formula	C₉H₁₀O₄
FormulaWt.	182.17
ChemicalName	3,4-Dihydroxybenzoicacidethylester
IUPACName	ethyl3,4-dihydroxybenzoate
Synonym	Ethyl3,4-dihydroxybenzoate
MeltingPoint	131-136°C
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	P7060InfoSheetPDF

References

StumpfC,FanQ,HintermannC,etal.Anti-inflammatoryeffectsofdanshenonhumanvascularendothelialcellsinculture.AmJChinMed.2013;41(5):1065-77.PMID:24117069.

Garcia-AlvarezMC,MoussaI,NjomnangSohP,etal.BothplantsSebastianiachamaeleafromNigerandChrozophorasenegalensisfromSenegalusedinAfricantraditionalmedicineinmalariatreatmentshareasameactiveprinciple.JEthnopharmacol.2013Oct7;149(3):676-84.PMID:23906782.

KuriyamaI,NakajimaY,NishidaH,etal.InhibitoryeffectsoflowmolecularweightpolyphenolicsfromInonotusobliquusonhumanDNAtopoisomeraseactivityandcancercellproliferation.MolMedRep.2013Aug;8(2):535-42.PMID:23799608.

MuleyMM,ThakareVN,PatilRR,etal.Ameliorationofcognitive,motorandendogenousdefensefunctionswithsilymarin,piracetamandprotocatechuicacidinthecerebralglobalischemicratmodel.LifeSci.2013Jul19;93(1):51-7.PMID:23743171.

StojkovićDS,ZivkovićJ,SokovićM,etal.AntibacterialactivityofVeronicamontanaL.extractandofprotocatechuicacidincorporatedinafoodsystem.FoodChemToxicol.2013May;55:209-13.PMID:23333716.

LiJ,DengY,YuanC,etal.Antioxidantandquinonereductase-inducingconstituentsofblackchokeberry(Aroniamelanocarpa)fruits.JAgricFoodChem.2012Nov21;60(46):11551-9.PMID:23131110.

LinHH,ChenJH,ChouFP,etal.Protocatechuicacidinhibitscancercellmetastasisinvolvingthedown-regulationofRas/Akt/NF-κBpathwayandMMP-2productionbytargetingRhoBactivation.BrJPharmacol.2011Jan;162(1):237-54.PMID:20840540.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂