Pyrantelpamoateisamixtureofpyrantel,athiophene,andpamoicacid.Thiscombinationexhibitsanti-parasitic/anti-helminthicactivities.Pyrantelpamoateactsasadepolarizingneuromuscularjunctionblocker,activatingnicotinicacetylcholinereceptors(nAChRs)attheneuromuscularjunctionandinducingmuscularparalysis.Pyrantelpamoateisusedtotreatworminfectionsinhumansandanimals.
| CasNo. | 22204-24-6 |
|---|---|
| Purity | ≥98% |
| Formula | C23H16O6•C11H14N2S |
| FormulaWt. | 594.68 |
| ChemicalName | (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)-ethenyl]pyrimidinepamoate |
| IUPACName | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylicacid;1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine |
| Synonym | Pyrantelembonate;Antiminth;Cobantril;Earlybird;Helmex;Piranver |
| MeltingPoint | 266-267°C |
| Solubility | Insolubleinwater. |
| Appearance | YellowtoTanSolid |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | P9668MSDSPDF |
|---|---|
| InfoSheet | P9668InfoSheetPDF |
ReinemeyerCR,HutchensDE,EckbladWP,etal.Dose-confirmationstudiesofthecestocidalactivityofpyrantelpamoatepasteinhorses.VetParasitol.2006Jun15;138(3-4):234-9.PMID:16530970.
ClarkJN,DaurioCP,PlueRE,etal.Efficacyofivermectinandpyrantelpamoatecombinedinachewableformulationagainstheartworm,hookworm,andascaridinfectionsindogs.AmJVetRes.1992Apr;53(4):517-20.PMID:1586021.
