LKT/NORFLOXACIN/N5768/5 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/NORFLOXACIN/N5768/5 g

LKT/NORFLOXACIN/N5768/5 g

商品编号： N5768-5g

品牌： lktlabs

市场价： ¥1340.00

美元价： 804.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDN5768

CasNo.70458-96-7

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Norfloxacinisafirstgenerationfluoroquinoloneantibioticthatexhibitsantibacterial,anti-inflammatory,andanticanceractivities.NorfloxacininhibitsDNAgyraseandtopoisomeraseIV;itisclinicallyusedtotreaturinarytractinfectionsandprostatitis.Inneutrophilsfromcirrhoticsubjects,norfloxacinincreasesexpressionofIL-10andhemeoxygenase1(HO-1)anddecreasesexpressionofpro-inflammatorycytokines.Additionally,whencomplexedwithgold(III),norfloxacinbindsDNAandinhibitscellularproliferationinseveralcancercelllines.

ProductInfo

CasNo.	70458-96-7
Purity	≥98%
Formula	C₁₆H₁₈FN₃O₃
FormulaWt.	319.33
ChemicalName	1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylicacid
IUPACName	1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylicacid
Synonym	Baccidal;Sebercim
MeltingPoint	227-228°C
Solubility	Solyat25oC(mg/ml):water0.28;methanol0.98;ethanol1.9.
Appearance	Yellowishwhitecrystalpowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	N5768InfoSheetPDF

References

GouveaLR,GarciaLS,LachterDR,etal.Atypicalfluoroquinolonegold(III)chelatesaspotentialanticanceragents:relevanceofDNAandproteininteractionsfortheirmechanismofaction.EurJMedChem.2012Sep;55:67-73.PMID:22835721.

Gómez-HurtadoI,ZapaterP,BellotP,etal.Interleukin-10-mediatedhemeoxygenase1-inducedunderlyingmechanismininflammatorydown-regulationbynorfloxacinincirrhosis.Hepatology.2011Mar;53(3):935-44.PMID:21374664.

PadeĭskaiaEN.Norfloxacin:morethan20yearsofclinicaluse,theresultsandplaceamongfluoroquinolonesinmodernchemotherapyforinfections.AntibiotKhimioter.2003;48(9):28-36.PMID:15002177.

DrlicaK,ZhaoX.DNAgyrase,topoisomeraseIV,andthe4-quinolones.MicrobiolMolBiolRev.1997Sep;61(3):377-92.PMID:9293187.

HoYB,ZakariaMP,LatifPA,SaariN.OccurrenceofveterinaryantibioticsandprogesteroneinbroilermanureandagriculturalsoilinMalaysia.SciTotalEnviron.2014Aug1;488-489:261-267.PMID:24836135.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂