LKT/NORFLOXACIN NICOTINATE/N5769/1 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/NORFLOXACIN NICOTINATE/N5769/1 g

LKT/NORFLOXACIN NICOTINATE/N5769/1 g

商品编号： N5769-1g

品牌： lktlabs

市场价： ¥740.00

美元价： 444.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDN5769

CasNo.118803-81-9

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Norfloxacinisafirstgenerationfluoroquinoloneantibioticthatexhibitsantibacterial,anti-inflammatory,andanticanceractivities.NorfloxacininhibitsDNAgyraseandtopoisomeraseIV;itisclinicallyusedtotreaturinarytractinfectionsandprostatitis.Inneutrophilsfromcirrhoticsubjects,norfloxacinincreasesexpressionofIL-10andhemeoxygenase1(HO-1)anddecreasesexpressionofpro-inflammatorycytokines.Additionally,whencomplexedwithgold(III),norfloxacinbindsDNAandinhibitscellularproliferationinseveralcancercelllines.

ProductInfo

CasNo.	118803-81-9
Purity	≥98%
Formula	C₁₆H₁₈FN₃O₃•C₆H₅NO₂
FormulaWt.	442.44
IUPACName	1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylicacid;pyridine-3-carboxylicacid
MeltingPoint	220-227°C
Solubility	Solubleinwater.
Appearance	White/SlightYellowCrystalPowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	N5769InfoSheetPDF

References

GouveaLR,GarciaLS,LachterDR,etal.Atypicalfluoroquinolonegold(III)chelatesaspotentialanticanceragents:relevanceofDNAandproteininteractionsfortheirmechanismofaction.EurJMedChem.2012Sep;55:67-73.PMID:22835721.

Gómez-HurtadoI,ZapaterP,BellotP,etal.Interleukin-10-mediatedhemeoxygenase1-inducedunderlyingmechanismininflammatorydown-regulationbynorfloxacinincirrhosis.Hepatology.2011Mar;53(3):935-44.PMID:21374664.

PadeĭskaiaEN.Norfloxacin:morethan20yearsofclinicaluse,theresultsandplaceamongfluoroquinolonesinmodernchemotherapyforinfections.AntibiotKhimioter.2003;48(9):28-36.PMID:15002177.

DrlicaK,ZhaoX.DNAgyrase,topoisomeraseIV,andthe4-quinolones.MicrobiolMolBiolRev.1997Sep;61(3):377-92.PMID:9293187.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂