LKT/OLIGOMYCIN B/O4532/5 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/OLIGOMYCIN B/O4532/5 mg

LKT/OLIGOMYCIN B/O4532/5 mg

商品编号： O4532-5mg

品牌： lktlabs

市场价： ¥7000.00

美元价： 4200.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDO4532

CasNo.11050-94-5

Purity≥97%,TLC,HPLC

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

OligomycinBisamacrolideantibioticinitiallyproducedbyseveralspeciesofStreptomyces.OligomycinBinhibitsmitochondrialF1F0ATPsynthase,bindingtheF0subunit,inhibitingATPsynthesis;itdisplaysantibacterialefficacyagainstavarietyofbacteria.Inmyocardialtissue,oligomycinBdecreasesATPconcentrationsandcontractilefunctionundernormoxicconditions,butinsteaddecreasestheATPdepletionrateduringischemicorhypoxicconditions.WhenadmiNISTeredinlargedoses,oligomycinBcauseshypertension,bradycardia,increasedarterialPO2,andmetabolicacidosis.OligomycinBinhibitsmitochondrialfunctionandisoftenusedtomimichypoxia-inducedconditions.

ProductInfo

CasNo.	11050-94-5
Purity	≥97%,TLC,HPLC
Formula	C₄₅H₇₂O₁₂
FormulaWt.	805.05
IUPACName	(1R,4S,5E,5"R,6"R,7E,10S,11R,12S,14R,15S,16S,18R,19S,20R,21E,25S,26R,27R,29S)-4-ethyl-11,12,15,19-tetrahydroxy-6"-[(2S)-2-hydroxypropyl]-5",10,12,14,16,18,20,26,29-nonamethylspiro[24,28-dioxABIcyclo[23.3.1]nonacosa-5,7,21-triene-27,2"-oxane]-3",13,17,23-tetrone
MeltingPoint	156-164°C
Solubility	SolubleinDMSO,ethanol,acetone.
Appearance	Whitepowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

MSDS	O4532MSDSPDF
InfoSheet	O4532InfoSheetPDF

References

GroverGJ,MalmJ.PharmacologicalprofileoftheselectivemitochondrialF1F0ATPhydrolaseinhibitorBMS-199264inmyocardialischemia.CardiovascTher.2008Winter;26(4):287-96.PMID:19035880.

GroverGJ,AtwalKS,SlephPG,etal.ExcessiveATPhydrolysisinischemicmyocardiumbymitochondrialF1F0-ATPase:effectofselectivepharmacologicalinhibitionofmitochondrialATPasehydrolaseactivity.AmJPhysiolHeartCircPhysiol.2004Oct;287(4):H1747-55.Erratumin:AmJPhysiolHeartCircPhysiol.2006Jul;291(1):H484.PMID:15371268.

KoosBJ,SameshimaH,PowerGG.Fetalbreathingmovement,sleepstateandcardiovascularresponsestoaninhibitorofmitochondrialATPaseinsheep.JDevPhysiol.1986Feb;8(1):67-75.PMID:2937831.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂