Description
Oxiconazole is an imidazole antifungal and anti-parasitic compound. Oxiconazole inhibits ergosterol synthesis, preventing formation of cell walls and displaying antimicrobial activity against Candida and Leishmania.
Oxiconazole is an imidazole antifungal and anti-parasitic compound. Oxiconazole inhibits ergosterol synthesis, preventing formation of cell walls and displaying antimicrobial activity against Candida and Leishmania.
| Cas No. | 64211-46-7 |
|---|---|
| Purity | ≥98% |
| Formula | C18H13Cl4N3O • HNO3 |
| Formula Wt. | 492.15 |
| Chemical Name | (Z)-1-(2,4-Dichloropheyl)-2-(1H-imidazol-1-yl)- ethenone O-[(2,4)-dichlorophenyl)methyl]oxime mononitrate |
| IUPAC Name | (Z)-1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-ylethanimine;nitric acid |
| Synonym | Oxistat; Myfungar; Oceral |
| Melting Point | 137-138°C |
| Solubility | Soluble in methanol. |
| Appearance | Yellowish to white crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | O9234 MSDS PDF |
|---|---|
| Info Sheet | O9234 Info Sheet PDF |
Kalra MG, Higgins KE, Kinney BS. Intertrigo and secondary skin infections. Am Fam Physician. 2014 Apr 1;89(7):569-73. PMID: 24695603.
Jerajani HR, Amladi ST, Bongale R, et al. Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study. Indian J Dermatol Venereol Leprol. 2000 Jul-Aug;66(4):188-92. PMID: 20877072.
Gebre-Hiwot A, Frommel D. The in-vitro anti-leishmanial activity of inhibitors of ergosterol biosynthesis. J Antimicrob Chemother. 1993 Dec;32(6):837-42. PMID: 8144423.