Oxytetracycline is a tetracycline antibiotic that exhibits broad spectrum antibacterial and anticancer efficacy; it is commonly used in veterinary medicine. Oxytetracycline inhibits t-RNA binding to ribosomes and inhibits proliferation of adenocarcinoma cells.
| Cas No. | 79-57-2 |
|---|---|
| Purity | ≥96% |
| Formula | C22H24N2O9 |
| Formula Wt. | 460.43 |
| Chemical Name | [4S-(4α,,4aα,5α,,5aα,,6β,12aα,)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydrothacenecarboxamide |
| IUPAC Name | (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
| Synonym | Adamycin; Geotilin;Terramycin |
| Melting Point | 184-185°C |
| Solubility | Insoluble in water (~0.24 mg/mL). Ethanol (15 mg/mL). |
| Appearance | Yellow powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | O9396 MSDS PDF |
|---|---|
| Info Sheet | O9396 Info Sheet PDF |
Strobel H, Lauseker M, Forbes AB. Targeted antibiotic treatment of lame sheep with footrot using either oxytetracycline or gamithromycin. Vet Rec. 2014 Jan 11;174(2):46. PMID: 24362004.
Shao J, Feng G. Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Chin J Cancer Res. 2013 Dec;25(6):662-70. PMID: 24385693.
Strel'tsov SA, Kukhanova MK, Gurskiĭ GV, et al. Oxytetracycline binding to E. coli ribosomes. Mol Biol (Mosk). 1975 Nov-Dec;9(6):910-21. PMID: 778591.
