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当前位置: 首页 > 产品中心 > clinical_research > LKT/PHENYL ISOTHIOCYANATE/P2513/50 g
商品详细LKT/PHENYL ISOTHIOCYANATE/P2513/50 g
LKT/PHENYL ISOTHIOCYANATE/P2513/50 g
LKT/PHENYL ISOTHIOCYANATE/P2513/50 g
商品编号: P2513-50g
品牌: lktlabs
市场价: ¥980.00
美元价: 588.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Phenylisothiocyanate(ITC)exhibitsantibiotic,anti-angiogenic,anti-inflammatory,antioxidative,anticancerchemotherapeutic,andchemopreventiveactivities.PhenylisothiocyanatedisplaysantibacterialefficacyagainstEscherichiaandStaphylococcus,alteringmembranefunctionandinducingcelldeath.Inothercellularmodels,thiscompounddownregulatesexpressionofVEGFandinflammatorycytokinesandincreasesexpressionofIL-2andTIMP.Additionally,phenylisothiocyanatedecreasesPMA-inducedsuperoxideanionlevels,inhibitslipidperoxidation,scavengeshydroxylrADIcals,anddecreasesformationandnumberofsolidtumorsinanimalmodels.LikeotherITCs,thiscompoundalsoactsasaphaseIIenzymeinducer.

ProductInfo

CasNo.

103-72-0

Purity

≥98%

Formula

C7H5NS

FormulaWt.

135.19

ChemicalName

Isothiocyanatobenzene

IUPACName

isothiocyanatobenzene

Synonym

PITC;Isothiocyanatobenzene;Phenylmustardoil;Thiocarbanil

MeltingPoint

-21°C

Solubility

Insolubleinwater.

Appearance

greenliquid

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

InfoSheet

P2513InfoSheetPDF

References

AbreuAC,BorgesA,SimõesLC,etal.AntibacterialactivityofphenylisothiocyanateonEscherichiacoliandStaphylococcusaureus.MedChem.2013Aug;9(5):756-61.PMID:22974327.

ThejassP,KuttanG.Inhibitionofendothelialcelldifferentiationandproinflammatorycytokineproductionduringangiogenesisbyallylisothiocyanateandphenylisothiocyanate.IntegrCancerTher.2007Dec;6(4):389-99.PMID:18048887.

ManeshC,KuttanG.Anti-tumourandanti-oxidantactivityofnaturallyoccurringisothiocyanates.JExpClinCancerRes.2003Jun;22(2):193-9.PMID:12866569.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂