Cheirolinisanisothiocyanate(ITC)thatexhibitsantioxidativeactivity.Cheirolinisasulfonylanalogofiberin.LikeothersITCs,cheirolininducesphaseIIenzymes.Invitro,cheirolinincreasesactivationandexpressionofNrf2aswellasexpressionofhemeoxygenase1(HO-1)andγ-glutamylcysteinesynthetase.
| CasNo. | 505-34-0 |
|---|---|
| Purity | ≥97% |
| Formula | C5H9NO2S2 |
| FormulaWt. | 179.26 |
| ChemicalName | 1-Isothiocyanato-3-(methylsulfonyl)-propane |
| IUPACName | 1-isothiocyanato-3-methylsulfonylpropane |
| MeltingPoint | 47.5°C |
| Solubility | Slightlysolubleinwater,ether;freelysolubleinalcohol,chloroform,ethylacetate. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C2816InfoSheetPDF |
|---|
ErnstIM,PalaniK,EsatbeyogluT,etal.SynthesisandNrf2-inducingactivityoftheisothiocyanatesiberverin,iberinandcheirolin.PharmacolRes.2013Apr;70(1):155-62.PMID:23403058.
