Coumestrolisaphytoestrogenfoundinvariousplantsourcessuchassoy,spinach,andclover;itexhibitsestrogenic,anti-inflammatory,immunomodulatory,anti-osteoporotic,andantidepressantactivities.CoumestrolactsasanagoNISTatERβandinhibitsaromataseand3α-hydroxysteroiddehydrogenase.Coumestroldecreasesimmobilityinanimalsundergoingtheforcedswimtest.Additionally,thiscompounddecreaseslevelsofTNF-α,IL-1β,IL-6,andRANKL,limitsTcelldifferentiationandactivation,andsuppressesformationofosteoclastsinvitro.
| CasNo. | 479-13-0 |
|---|---|
| Purity | ≥96% |
| Formula | C15H8O5 |
| FormulaWt. | 268.2 |
| ChemicalName | 3,9-Dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one |
| IUPACName | 3,9-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one |
| Synonym | Cumoesterol,Cumoestrol,Cumostrol |
| MeltingPoint | 385°C |
| Solubility | Insolubleinwater.Slightlysolubleinmethanol,ethanolorchloroform. |
| Appearance | LightBrownPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | C5680MSDSPDF |
|---|---|
| InfoSheet | C5680InfoSheetPDF |
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