Cytochalasin C is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin C inhibits motility of spermatozoa in vitro. This compound also increases transcription of TGF-β, collagenase, fibronectin, and procollagens 1 and 2 in vitro.
| Cas No. | 22144-76-9 |
|---|---|
| Purity | ≥98%, TLC |
| Formula | C30H37NO6 |
| Formula Wt. | 507.62 |
| Melting Point | 260°C (dec) |
| Solubility | Dichloromethane , Ethyl acetate |
| Appearance | White Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | C9880 Info Sheet PDF |
|---|
Varedi M, Ghahary A, Scott PG, et al. Cytoskeleton regulates expression of genes for transforming growth factor-beta 1 and extracellular matrix proteins in dermal fibroblasts. J Cell Physiol. 1997 Aug;172(2):192-9. PMID: 9258340.
Glinsukon T, Sinlapanapaporn S, Chulasamaya M. Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro. Res Commun Chem Pathol Pharmacol. 1986 Feb;51(2):265-8. PMID: 3961270.
