LKT/PROTOPANAXADIOL/P6957/25 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/PROTOPANAXADIOL/P6957/25 mg

LKT/PROTOPANAXADIOL/P6957/25 mg

商品编号： P6957-25mg

品牌： lktlabs

市场价： ¥12280.00

美元价： 7368.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDP6957

CasNo.7755-01-3

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

ProtopanaxADIolisatriterpenesapogeninoriginallyfoundinspeciesofPanax(ginseng)thatexhibitsanticancer,neuromodulatory,neuroprotective,andantioxidativeactivities.ProtopanaxadiolpreventsbreakdownofvitaminD3andactsasanantagoNISTatGABA-Areceptors.Protopanaxadiolalsoinhibitsproliferationofcolorectalcancercellsandinducesmitochondria-andcaspase-dependentapoptosisinlungadenocarcinomacellsbydecreasingthemitochondrialmembranepotentialandincreasingreleaseofcytochromeC,activationofcaspases3and9,andcleavageofPARP.Inanimalmodelsofcerebralischemia,protopanaxadiolincreasesactivityofsuperoxidedismutaseandNa+/K+ATPases,stimulatesexpressionofBcl-2,anddecreasesinfarctsizeandneurologicaldeficits.

ProductInfo

CasNo.	7755-01-3
Purity	≥98%
Formula	C₃₀H₅₂O₃
FormulaWt.	460.73
IUPACName	(3S,8R,9R,10R,12R,13R,14S,17S)-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol
Appearance	WhitePowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

MSDS	P6957MSDSPDF
InfoSheet	P6957InfoSheetPDF

References

DebS,ChinMY,AdomatH,etal.Ginsenoside-mediatedblockadeof1α,25-dihydroxyvitaminD3inactivationinhumanliverandintestineinvitro.JSteroidBiochemMolBiol.2014May;141:94-103.PMID:24486455.

XuH,YuX,QuS,etal.ProtectiveeffectofPanaxquinquefolium20(S)-protopanaxadiolsaponins,isolatedfromPanaquinquefolium,onpermanentfocalcerebralischemicinjuryinrats.ExpTherMed.2014Jan;7(1):165-170.PMID:24348784.

ZhengY,NanH,HaoM,etal.Antiproliferativeeffectsofprotopanaxadiolginsenosidesonhumancolorectalcancercells.BiomedRep.2013Jul;1(4):555-558.PMID:24648985.

ZhangYL,ZhangR,XuHL,etal.20(S)-protopanaxadioltriggersmitochondrial-mediatedapoptosisinhumanlungadenocarcinomaA549cellsviainhibitingthePI3K/Aktsignalingpathway.AmJChinMed.2013;41(5):1137-52.PMID:24117074.

LeeBH,ChoiSH,ShinTJ,etal.EffectsofGinsenosideMetabolitesonGABAAReceptor-MediatedIonCurrents.JGinsengRes.2012Jan;36(1):55-60.PMID:23717104.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂