Corticotropin-releasingfactor(CRF)isanendogenousneuropeptidehormonethatisinvolvedinstressresponses,depression,anxiety,andothermooddisorders.CRFbindsCRFreceptors,stimulatingreleaseofadrenocorticotropichormone(ACTH),cortisol,dehydroepiandrosterone(DHEA),andβ-endorphin.CRFalsomodulatesthedurationofpregnancyandstimulatesreleaseofdehydroepiandrosterone(DHEA)inthefetaladrenalgland.HighlevelsofCRFmaybeusedasabioMarkertodetectAlzheimer’sdiseaseormajordepression.
| Purity | ≥95% |
|---|---|
| Formula | C205H339N59O63S |
| FormulaWt. | 4370.41 |
| Synonym | CRF;CRH |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C5774InfoSheetPDF |
|---|
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