Description
Cysteamineisanaminothiolthatexhibitsantioxidative,anti-metastatic,antidepressant,neuromodulatory,andantipsychoticactivities.Cysteamineisusedinresearchmodelstoinduceulcerformation;clinically,ittreatscystinosisandotherdisordersofcysteineexcretion.CysteamineisalsoacomponentusedtoformcoenzymeA(CoA).Inanimalmodelsofpancreaticcancer,cysteaminedecreasesactivityofmatrixmetalloproteinases(MMPs)andsuppressesmetastasis.CysteaminedecreasesimmobilitytimeinanimalsundergoingtheforcedswimtestandtailsUSPensiontestandincreaseslevelsofBDNF.Thiscompoundalsodisplayspotentialbenefitinpre-clinicalmodelsofschizophrenia.Additionally,cysteamineimprovesmotordeficitsandincreasessurvivalinanimalmodelsofHuntington’sdisease.
References
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