Description
DAPTisaγ-secretaseinhibitorthatsuppressesNotchsignalingandexhibitsneuroprotectiveandanticanceractivities.DAPTinhibitsproliferationofcancerstemcells.
DAPTisaγ-secretaseinhibitorthatsuppressesNotchsignalingandexhibitsneuroprotectiveandanticanceractivities.DAPTinhibitsproliferationofcancerstemcells.
CasNo. | 208255-80-5 |
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Purity | ≥98% |
Formula | C23H26F2N2O4 |
FormulaWt. | 432.47 |
IUPACName | 2-Methyl-2-propanyl(2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate |
Synonym | GSI-IX |
Appearance | Whitetooffwhitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | D0260InfoSheetPDF |
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LiuJ,MaoZ,HuangJ,etal.BlockingtheNOTCHpathwaycaninhibitthegrowthofCD133-positiveA549cellsandsensitizetochemotherapy.BiochemBiophysResCommun.2014Feb21;444(4):670-5.PMID:24502949.