Description
DAPTisaγ-secretaseinhibitorthatsuppressesNotchsignalingandexhibitsneuroprotectiveandanticanceractivities.DAPTinhibitsproliferationofcancerstemcells.
DAPTisaγ-secretaseinhibitorthatsuppressesNotchsignalingandexhibitsneuroprotectiveandanticanceractivities.DAPTinhibitsproliferationofcancerstemcells.
| CasNo. | 208255-80-5 |
|---|---|
| Purity | ≥98% |
| Formula | C23H26F2N2O4 |
| FormulaWt. | 432.47 |
| IUPACName | 2-Methyl-2-propanyl(2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate |
| Synonym | GSI-IX |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | D0260InfoSheetPDF |
|---|
LiuJ,MaoZ,HuangJ,etal.BlockingtheNOTCHpathwaycaninhibitthegrowthofCD133-positiveA549cellsandsensitizetochemotherapy.BiochemBiophysResCommun.2014Feb21;444(4):670-5.PMID:24502949.