Thissyntheticpeptideanalogofdermorphinactivatesμ-opioidreceptors(μORs)andδ-opioidreceptors(δORs).LikeothersimilaropioidagoNISTs,thispeptideaffectslearningandmemoryaswellasmotoractivityandexhibitsneuromodulatoryandantinociceptive/analgesicactivities.
| Purity | ≥95% |
|---|---|
| Formula | C44H59N11O10 |
| FormulaWt. | 902.03 |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | D1770InfoSheetPDF |
|---|
VonhofS,BaroneFC,PriceWJ,etal.ReceptorbindingandBIOLOGicalactivityofthedermorphinanalogTyr-D-Arg(2)-Phe-Sar(TAPS).EurJPharmacol.2001Mar23;416(1-2):83-93.PMID:11282116.
UkaiM,KobayashiT,MoriK,etal.AttenuationofmemorywithTyr-D-Arg-Phe-beta-Ala-NH2,anoveldermorphinanalogwithhighaffinityformu-opioidreceptors.EurJPharmacol.1995Dec20;287(3):245-9.PMID:8991797.
PaakkariP,PaakkariI,VonhofS,etal.DermorphinanalogTyr-D-Arg2-Phe-sarcosine-inducedopioidanalgesiaandrespiratorystimulation:theroleofmu1-receptors?JPharmacolExpTher.1993Aug;266(2):544-50.PMID:8394909.
