LKT/DEXTROMETHORPHAN HYDROBROMIDE HYDRATE/D1792/50 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/DEXTROMETHORPHAN HYDROBROMIDE HYDRATE/D1792/50 g

LKT/DEXTROMETHORPHAN HYDROBROMIDE HYDRATE/D1792/50 g

商品编号： D1792-50g

品牌： lktlabs

市场价： ¥7700.00

美元价： 4620.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDD1792

CasNo.6700-34-1

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Dextromethorphanexhibitsanti-tussive,hallucinogenic,neuromodulatory,neuroprotective,anticonvulsant/antiepileptic,andanti-osteoporoticactivities.DextromethorphanactsasafullantagoNISTatSEROtonintransporters(SERTs),norepinephrinetransporters(NETs),α3β4,α4β2,andα7nicotinicacetylcholinereceptors(nAChRs),andNADPHoxidase;italsoactsasaweakantagonistatNMDAreceptors.Additionally,dextromethorphanactsasafullagonistatσ1/2receptorsandasaweakagonistatμ/κ/δopioidreceptors.Dextromethorphaniscommonlyusedinover-the-countercoughmedicines.InanimalmodelsofParkinson’sdisease,dextromethorphaninhibitsendotoxin-induceddopaminergicneurodegeneration.Inelectroshockassays,thiscompoundinhibitsthedevelopmentofseizures.DextromethorphanalsoinhibitsRANKL-inducedosteoclastogenesisandpreventsbonelossinvivo.CHECKBUYERINFO–THISPRODUCTHASBEENKNOWNFORRECREATIONALUSE.

ProductInfo

CasNo.	6700-34-1
Purity	≥98%
Formula	C₁₈H₂₅NO•HBr•H₂O
FormulaWt.	370.3
ChemicalName	D-(+)-3-methoxy-17-methyl-(9α,13α,14α)-morphinan
Synonym	()-3-Methoxy-N-methylmorphinon;delta-Methorphan
MeltingPoint	116-120°C
Solubility	Solubleinwater(15mg/mL).
Appearance	Whitepowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	D1792MSDSPDF
InfoSheet	D1792InfoSheetPDF

References

BurnsJM,BoyerEW.Antitussivesandsubstanceabuse.SubstAbuseRehABIl.2013Nov6;4:75-82.PMID:24648790.

WuK,LinTH,LiouHC,etal.DextromethorphaninhibitsosteoclastdifferentiationbysuppressingRANKL-inducednuclearfactor-κBactivation.OsteoporosInt.2013Aug;24(8):2201-14.PMID:23400250.

DamajMI,FloodP,HoKK,etal.Effectofdextrometorphananddextrorphanonnicotineandneuronalnicotinicreceptors:invitroandinvivoselectivity.JPharmacolExpTher.2005Feb;312(2):780-5.PMID:15356218.

ZhangW,WangT,QinL,etal.NeuroprotectiveeffectofdextromethorphanintheMPTPParkinson"sdiseasemodel:roleofNADPHoxidase.FASEBJ.2004Mar;18(3):589-91.PMID:14734632.

ChouYC,LiaoJF,ChangWY,etal.Bindingofdimemorfantosigma-1receptoranditsanticonvulsantandlocomotoreffectsinmice,comparedwithdextromethorphananddextrorphan.BrainRes.1999Mar13;821(2):516-9.PMID:10064839.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂