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当前位置: 首页 > 产品中心 > clinical_research > LKT/S-(U2212)-SULPIRIDE/S8345/10 g
商品详细LKT/S-(U2212)-SULPIRIDE/S8345/10 g
LKT/S-(U2212)-SULPIRIDE/S8345/10 g
LKT/S-(U2212)-SULPIRIDE/S8345/10 g
商品编号: S8345-10g
品牌: lktlabs
市场价: ¥3260.00
美元价: 1956.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Sulpiride is an antipsychotic that functions as an antagonist at D2/3 receptors and also upregulates and activates the GHB receptor. In vivo, sulpiride ameliorates increased impulsivity and attentional impairment in PFC-lesioned models of schizophrenia. Additionally, because dopamine inhibits prolactin release, sulpiride’s inhibition of dopamine results in increased concentrations of prolactin as well as melanocyte-stimulating hormone.

Product Info

Cas No.

23672-07-3

Purity

≥99%

Formula

C15H23N3O4S

Formula Wt.

341.43

IUPAC Name

N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide

Melting Point

178-180°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

Info Sheet

S8345 Info Sheet PDF

References

Valencia NA, Thompson DL Jr, Mitcham PB. Changes in plasma melanocyte-stimulating hormone, ACTH, prolactin, GH, LH, FSH, and thyroid-stimulating hormone in response to injection of sulpiride, thyrotropin-releasing hormone, or vehicle in insulin-sensitive and -insensitive mares. Domest Anim Endocrinol. 2013 May;44(4):204-12. PMID: 23571008.

Pezze MA, Dalley JW, Robbins TW. Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride. Psychopharmacology (Berl). 2009 Jan;202(1-3):307-13. PMID: 18985321.

Ratomponirina C, Gobaille S, Hodé Y, et al. Sulpiride, but not haloperidol, up-regulates gamma-hydroxybutyrate receptors in vivo and in cultured cells. Eur J Pharmacol. 1998 Apr 10;346(2-3):331-7. PMID: 9862377.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂