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当前位置: 首页 > 产品中心 > clinical_research > LKT/PREDNISONE/P7020/5 g
商品详细LKT/PREDNISONE/P7020/5 g
LKT/PREDNISONE/P7020/5 g
LKT/PREDNISONE/P7020/5 g
商品编号: P7020-5g
品牌: lktlabs
市场价: ¥2800.00
美元价: 1680.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Prednisoneisasyntheticcorticosteroid/glucocorticoidthatexhibitsnoBIOLOGicalactivityuntilconvertedtoitsactivemetabolite,prednisolone.Onceconverted,thiscompoundexhibitsanti-inflammatory,immunosuppressive,anti-allergic,neuroprotective,andanticancerchemotherapeuticactivities.PrednisoneisonecomponentoftheCHOPchemotherapeuticcocktailthatisclinicallyusedtotreatleukemiasandlymphomas;inanimalmodelsofsubarachnoidhemorrhage,CHOPinhibitsneuronalapoptosis.PrednisonealsoinhibitsexpressionofIL-6andisclinicallyusedtotreatrheumatoidarthritis.

ProductInfo

CasNo.

53-03-2

Purity

≥98%

Formula

C21H26O5

FormulaWt.

358.43

ChemicalName

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

IUPACName

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

Synonym

Ancortone;Colisone;Decortin;Hostacortine;Orasone;Paracort;Sone;Ultracorten

MeltingPoint

233-235°C(dec)

Solubility

Slightlysolubleinwaterandethanol(6.5mg/mL).

Appearance

Whitetopracticallywhite,odorlesscrystallinepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

P7020InfoSheetPDF

References

HoySM.Bendamustine:areviewofitsuseinthemanagementofchroniclymphocyticleukaemia,rituximab-refractoryindolentnon-Hodgkin"slymphomaandmultiplemyeloma.Drugs.2012Oct1;72(14):1929-50.PMID:22950536.

ClarkeL,KirwanJ.Efficacy,safetyandmechanismofactionofmodified-releaseprednisoneinrheumatoidarthritis.TherAdvMusculoskeletDis.2012Jun;4(3):159-66.PMID:22850902.

HeZ,OstrowskiRP,SunX,etal.CHOPsilencingreducesacutebraininjuryintheratmodelofsubarachnoidhemorrhage.Stroke.2012Feb;43(2):484-90.PMID:22180248.

MannsMP,StrassburgCP.Therapeuticstrategiesforautoimmunehepatitis.DigDis.2011;29(4):411-5.PMID:21894012.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂