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商品详细LKT/PROGESTERONE/P6854/5 g
LKT/PROGESTERONE/P6854/5 g
LKT/PROGESTERONE/P6854/5 g
商品编号: P6854-5g
品牌: lktlabs
市场价: ¥660.00
美元价: 396.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Progesteroneisanendogenoussteroidhormonethatactivatesprogesteronereceptors(PRs)andinhibitsmineralocorticoidreceptors(MRs),nicotinicacetylcholinereceptors(nAChRs),andσ1/2receptors.Progesteroneexhibitsneuroprotectiveactivity,inducingmyelinsheathformationandsupportingneurotransmission.Progesteronealsoplaysasignificantroleinreproductionandmammaryglanddevelopment.Clinically,thiscompoundisusedtopreventpretermbirthandisoccasionallyusedinhormonereplacementtherapy(HRT).

ProductInfo

CasNo.

57-83-0

Purity

≥98%

Formula

C21H30O2

FormulaWt.

314.47

ChemicalName

Pregn-4-ene-3,20-dione

IUPACName

(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Synonym

Corlutin;Gesterol;Luteol;Prolutone;Prolidon;Syngesterone;Utrogestan

MeltingPoint

128-132°C

Solubility

Insolubleinwater.Solubleinalcohol,acetoneordioxane.

Appearance

Whiteoralmostwhitecrystallinepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

P6854InfoSheetPDF

References

JohannessenM,FontanillaD,MavlyutovT,etal.AntagoNISTactionofprogesteroneatσ-receptorsinthemodulationofvoltage-gatedsodiumchannels.AmJPhysiolCellPhysiol.2011Feb;300(2):C328-37.Erratumin:AmJPhysiolCellPhysiol.2013Nov1;305(9):C997.PMID:21084640.

daFonsecaEB,BittarRE,CarvalhoMH,etal.Prophylacticadministrationofprogesteronebyvaginalsuppositorytoreducetheincidenceofspontaneouspretermbirthinwomenatincreasedrisk:arandomizedplacebo-controlleddouble-blindstudy.AmJObstetGynecol.2003Feb;188(2):419-24.PMID:12592250.

BaulieuE,SchumacherM.Progesteroneasaneuroactiveneurosteroid,withspecialreferencetotheeffectofprogesteroneonmyelination.Steroids.2000Oct-Nov;65(10-11):605-12.PMID:11108866.

RupprechtR,ReulJM,vanSteenselB,etal.Pharmacologicalandfunctionalcharacterizationofhumanmineralocorticoidandglucocorticoidreceptorligands.EurJPharmacol.1993Oct15;247(2):145-54.PMID:8282004.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂