Description
Cyclosporin H is a cyclosporin metabolite that inhibits the formyl peptide receptor but not calmodulin. Cyclosporin H lacks immunosuppressive activity but inhibits basophil activation.
LKT/CYCLOSPORIN H/C9614/5 mg
市场价：
¥9580.00
美元价：
5748.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product ID C9614
Cas No. 83602-39-5
Purity ≥96%
- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Product Info
| Cas No. | 83602-39-5 |
|---|---|
| Purity | ≥96% |
| Formula | C62H111N11O12 |
| Formula Wt. | 1202.61 |
| IUPAC Name | (3S,6S,9S,12R,15S,18S,21R,24S,30S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,22,25,28-decamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone |
| Synonym | Csh cyclosporin; Cyclosporine H |
| Melting Point | 162-167°C |
| Solubility | Soluble in DMSO, ethanol, Acetone, chloroform. |
| Appearance | White Crystalline Powder |
Shipping and Storage
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | C9614 MSDS PDF |
|---|---|
| Info Sheet | C9614 Info Sheet PDF |
References
Stenfeldt AL, Karlsson J, Wennerås C, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9. PMID: 17687636.
Yan P, Nanamori M, Sun M, et al. The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding. J Immunol. 2006 Nov 15;177(10):7050-8. PMID: 17082621.
de Paulis A, Ciccarelli A, de Crescenzo G, et al. Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine. J Allergy Clin Immunol. 1996 Jul;98(1):152-64. PMID: 8765829.
品牌介绍
LKT Labs
LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。
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