Eledoisin-related peptide (ERP) is a tachykinin analog of substance P. ERP binds neurokinin receptors, exhibiting analgesic and bronchoconstrictive activities. ERP alters pain thresholds in animal models of thermal pain. In other animal models, this peptide induces bronchoconstriction through direct activity on airway smooth muscle. Additionally, ERP inhibits M-currents and stimulates gastric acid secretion in vivo.
| Purity | ≥95% |
|---|---|
| Formula | C34H58N8O6S |
| Formula Wt. | 706.96 |
| Synonym | ERP |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | E4417 Info Sheet PDF |
|---|
Clint BD, Lipton JM, Giesecke AH Jr. Analgesic and cardiovascular effects of centrally administered substance P. Peptides. 1988 May-Jun;9(3):619-23. PMID: 2458573.
Goel V, Biggs DF. Comparison of the bronchoconstrictor and cardiovascular effects of some tachykinins in guinea pigs. Life Sci. 1987 Mar 9;40(10):1007-15. PMID: 2434817.
Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.
