Eledoisin-relatedpeptide(ERP)isatachykininanalogofsubstanceP.ERPbindsneurokininreceptors,exhibitinganalgesicandbronchoconstrictiveactivities.ERPalterspainthresholdsinanimalmodelsofthermalpain.Inotheranimalmodels,thispeptideinducesbronchoconstrictionthroughdirectactivityonairwaysmoothmuscle.Additionally,ERPinhibitsM-currentsandstimulatesgastricacidsecretioninvivo.
| Purity | ≥95% |
|---|---|
| Formula | C34H58N8O6S |
| FormulaWt. | 706.96 |
| Synonym | ERP |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | E4417InfoSheetPDF |
|---|
ClintBD,LiptonJM,GieseckeAHJr.AnalgesicandcardiovasculareffectsofcentrallyadmiNISTeredsubstanceP.Peptides.1988May-Jun;9(3):619-23.PMID:2458573.
GoelV,BiggsDF.Comparisonofthebronchoconstrictorandcardiovasculareffectsofsometachykininsinguineapigs.LifeSci.1987Mar9;40(10):1007-15.PMID:2434817.
HolsteinB,CederbergC.EffectsoftachykininsongastricacidandpepsinsecretionandongastricoutflowintheAtlanticcod,Gadusmorhua.AmJPhysiol.1986Mar;250(3Pt1):G309-15.PMID:2420206.
