NivalenolisaFusariumtypeBtrichothecenemycotoxin.Nivalenoliscytotoxictoleukocytes,inhibitingcellproliferation,increasingIL-8secretion,anddecreasingMCP-1secretioninanNF-κB-dependentmanner.InmacrophagesandJurkatTcells,nivalenolincreasescytochromecreleaseanddegradationofBcl-2,stimulatingcaspase3-mediatedapoptosis.Additionally,nivalenolinducesthebreakdownofpolyribosomesandinhibitspolypeptidechaininitiationineukaryotes.
| CasNo. | 23282-20-4 |
|---|---|
| Purity | ≥99%,TLC |
| Formula | C15H20O7 |
| FormulaWt. | 312.32 |
| MeltingPoint | 127-130°C |
| Solubility | DMSO,Methanol,dichloromethane.Slightlysolubleinwater. |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | N3584MSDSPDF |
|---|---|
| InfoSheet | N3584InfoSheetPDF |
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