Octopamineisanendogenousneuromodulatoryaminethatcanalsobefoundinplantsources.Octopaminestimulatesmotoractivityandmuscularcontractionsintheforegutatlowdosesanddecreasescontractionsathighdoses.OctopaminealsoinhibitsLPS-stimulatedreleaseofNOinaβ-adrenergicreceptor-dependentmannerinastroglia.Additionally,thispeptidedecreasesjuvenilehormonedegradationinfemaleDrosophila.
| CasNo. | 770-05-8 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11NO2•HCl |
| FormulaWt. | 189.64 |
| ChemicalName | DL-α-(Aminomethyl)-p-hydroxybenzenemethanolhydrochloride |
| IUPACName | 4-(2-amino-1-hydroxyethyl)phenol;hydrochloride |
| Synonym | Epirenor;Norden;Norfen;Norphen. |
| MeltingPoint | 170°C(dec) |
| Solubility | Solubleinwater. |
| Appearance | Off-WhiteFinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | O0977MSDSPDF |
|---|---|
| InfoSheet | O0977InfoSheetPDF |
RandD,KNEBelD,AyaliA.Theeffectofoctopamineonthelocuststomatogastricnervoussystem.FrontPhysiol.2012Jul20;3:288.PMID:22934040.
D"AndreaG,D"ArrigoA,FacchinettiF,etal.Octopamine,unlikeothertraceamines,inhibitsresponsesofastroglia-enrichedculturestolipopolysaccharideviaaβ-adrenoreceptor-mediatedmechanism.NeurosciLett.2012May23;517(1):36-40.PMID:22507691.
GruntenkoNE,KarpovaEK,AlekseevAA,etal.Effectsofoctopamineonreproduction,juvenilehormonemetabolism,dopamine,and20-hydroxyecdysonecontentsinDrosophila.ArchInsectBiochemPhysiol.2007Jun;65(2):85-94.PMID:17523171.
