Octopamine is an endogenous neuromodulatory amine that can also be found in plant sources. Octopamine stimulates motor activity and muscular contractions in the foregut at low doses and decreases contractions at high doses. Octopamine also inhibits LPS-stimulated release of NO in a β-adrenergic receptor-dependent manner in astroglia. Additionally, this peptide decreases juvenile hormone degradation in female Drosophila.
| Cas No. | 770-05-8 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11NO2 • HCl |
| Formula Wt. | 189.64 |
| Chemical Name | DL-α-(Aminomethyl)-p-hydroxybenzenemethanolhydrochloride |
| IUPAC Name | 4-(2-amino-1-hydroxyethyl)phenol;hydrochloride |
| Synonym | Epirenor; Norden; Norfen; Norphen. |
| Melting Point | 170°C (dec) |
| Solubility | Soluble in water. |
| Appearance | Off-White Fine Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | O0977 MSDS PDF |
|---|---|
| Info Sheet | O0977 Info Sheet PDF |
Rand D, Knebel D, Ayali A. The effect of octopamine on the locust stomatogastric nervous system. Front Physiol. 2012 Jul 20;3:288. PMID: 22934040.
D'Andrea G, D'Arrigo A, Facchinetti F, et al. Octopamine, unlike other trace amines, inhibits responses of astroglia-enriched cultures to lipopolysaccharide via a β-adrenoreceptor-mediated mechanism. Neurosci Lett. 2012 May 23;517(1):36-40. PMID: 22507691.
Gruntenko NE, Karpova EK, Alekseev AA, et al. Effects of octopamine on reproduction, juvenile hormone metabolism, dopamine, and 20-hydroxyecdysone contents in Drosophila. Arch Insect Biochem Physiol. 2007 Jun;65(2):85-94. PMID: 17523171.
