LKT/OCTREOTIDE ACETATE/O1078/1 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/OCTREOTIDE ACETATE/O1078/1 mg

LKT/OCTREOTIDE ACETATE/O1078/1 mg

商品编号： O1078-1mg

品牌： lktlabs

市场价： ¥1700.00

美元价： 1020.00

产地：美国(厂家直采)

公司：

产品分类：多肽

公司分类： peptides

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDO1078

CasNo.79517-01-4

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Octreotideisasomatostatinpeptideanalogthatactsatsomatostatinreceptorsandinhibitsthereleaseofgrowthhormone.Octreotideexhibitsanticancer,anti-fibrotic,anti-inflammatory,andimmunomodulatoryactivities.OctreotideinhibitscoloncancercellgrowththroughthesuppressionofWnt/β-cateninsignaling.Octreotideinhibitshepaticstellatecellproliferation,downregulatingtheexpressionofTGF-β,α-SMA,Smad-4a,c-Jun,sp-1,ET-1,andcollagen;itisalsoprotectiveagainstfibrosisinanimalmodels.Additionally,octreotideinhibitsperipheralbloodmononuclearcellproliferation,decreasinglevelsofIL-6,IL-10,andIFN-γandproducingclinicalimprovementsinsubjectswithsystematiclupuserythematous.

ProductInfo

CasNo.	79517-01-4
Purity	≥95%
Formula	C₄₉H₆₆N₁₀O₁₀S₂•2C₂H₄O₂
FormulaWt.	1139.36
ChemicalName	D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamidecyclic(2->7)-disulfideacetate(salt)
IUPACName	10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Synonym	Sandostatin
Solubility	Solubleinmethanol.
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

MSDS	O1078MSDSPDF
InfoSheet	O1078InfoSheetPDF
Brochures	WNTBooklet

References

WangS,BaoZ,LiangQM,etal.Octreotidestimulatessomatostatinreceptor-inducedapoptosisofSW480coloncancercellsbyactivationofglycogensynthasekinase-3β,AWnt/β-cateninpathwaymodulator.Hepatogastroenterology.2013Oct;60(127):1639-46.PMID:24634935.

WangJ,WangL,SongG,etal.Themechanismthroughwhichoctreotideinhibitshepaticstellatecellactivity.MolMedRep.2013May;7(5):1559-64.PMID:23525276.

TugT,KaraH,KaraogluA,etal.Theeffectofoctreotide,ananalogofsomatostatin,onbleomycin-inducedinterstitialpulmonaryfibrosisinrats.DrugChemToxicol.2013Apr;36(2):181-6.PMID:22946449.

ZhangY,HuangW,LiF,etal.Octreotideforthetreatmentofsystemiclupuserythematosus:clinicaleffectsandaninvitrostudyonitstherapeuticmechanism.Lupus.2011Oct;20(11):1172-81.PMID:21979989.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂