Bromhexineisasyntheticderivativeofvasicinethatexhibitsmucolyticandantioxidativeactivities.BromhexineincreasesproductionofSEROusmucus,decreasesmucusviscosity,andhelpsciliatransportmucusoutofthelungs.Bromhexineisclinicallyusedtotreatrespiratorydisorderscharacterizedbyexcessivemucus.Additionally,bromhexinealsodecreasesproductionofROSinalveolarmacrophagesbymodulatingenzymaticactivity.
| CasNo. | 611-75-6 |
|---|---|
| Purity | ≥98% |
| Formula | C14H20Br2N2HCl |
| FormulaWt. | 412.60 |
| ChemicalName | 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl-benzenemethanaminehydrochloride |
| IUPACName | 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;hydrochloride |
| Synonym | Auxit;Bisolvon;Ophtosol;Quentan |
| MeltingPoint | 240-244°C |
| Solubility | Slightlysolubleinchloroform.Sparinglysolubleinethanolormethanol. |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | B6957MSDSPDF |
|---|---|
| InfoSheet | B6957InfoSheetPDF |
WinselK,GrollmussH,UngerU,etal.Modulationofalveolarmacrophageactivitybyambroxol,bromhexineandexogenousarachidonicacid.ZErkrAtmungsorgane.1985;165(2):149-62.PMID:3002048.
TakedaH,AbeY,MisawaM,etal.Theroleofvagalreflexinmechanismofsecretagogicactionofbromhexine.JpnJPharmacol.1984Aug;35(4):445-50.PMID:6503040.
