Description
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
| Cas No. | 702675-74-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H26IN7O2S |
| Formula Wt. | 591.47 |
| IUPAC Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| Synonym | BX795 |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | B9200 Info Sheet PDF |
|---|
Feldman RI, Wu JM, Polokoff MA, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem. 2005 May 20;280(20):19867-74. PMID: 15772071.