Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
Cas No. | 125-84-8 |
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Purity | ≥98% |
Formula | C13H16N2O2 |
Formula Wt. | 232.28 |
Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
Synonym | Aminoglutethimide; Cytadren; Elipten; Orimeten |
Melting Point | 149-150°C |
Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
Appearance | White Crystalline Powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | A5032 MSDS PDF |
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Info Sheet | A5032 Info Sheet PDF |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.