Diethylstilbestrolisasyntheticnon-steroidalestrogenthatexhibitsanticanceractivity.Diethylstilbestrolwaspreviouslyusedtotreatbreastcancer,prostatecancer,vaginitis,symptomsofmenopause,andinthepreventionofmiscarriage.Thiscompoundisnolongerclinicallyusedforthesepurposesandhassincebeenclassifiedasanendocrinedisrupter.
| CasNo. | 56-53-1 |
|---|---|
| Purity | ≥98% |
| Formula | C18H20O2 |
| FormulaWt. | 268.35 |
| ChemicalName | 4,4"-[(1E)-1,2-Diethyl-1,2-ethenediyl]bisphenol |
| IUPACName | 4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol |
| Synonym | Stilbestrol;DES;Apstil;CyrenA;Stilbetin |
| MeltingPoint | 169-172°C |
| Solubility | Solubleinalcohol,ether,chloroformorfattyoils.Insolubleinwater. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | D3218MSDSPDF |
|---|---|
| InfoSheet | D3218InfoSheetPDF |
IngleJN,AhmannDL,GreenSJ,etal.Randomizedclinicaltrialofdiethylstilbestrolversustamoxifeninpostmenopausalwomenwithadvancedbreastcancer.NEnglJMed.1981Jan1;304(1):16-21.PMID:7001242.
DieckmannWJ,DavisME,RynkiewiczLM,etal.DoestheadmiNISTrationofdiethylstilbestrolduringpregnancyhavetherapeuticvalue?AmJObstetGynecol.1953Nov;66(5):1062-81.PMID:13104505.
