4000-520-616
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当前位置: 首页 > 产品中心 > clinical_research > LKT/QUINESTROL/Q8135/250 mg
商品详细LKT/QUINESTROL/Q8135/250 mg
LKT/QUINESTROL/Q8135/250 mg
LKT/QUINESTROL/Q8135/250 mg
商品编号: Q8135-250mg
品牌: lktlabs
市场价: ¥2080.00
美元价: 1248.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Quinestrolisasyntheticestrogenhomologthatexhibitsanti-fertilityandcontraceptiveactivities.QuinestrolisanERagoNISTandisalsousedinHRT.Quinestrolisdisplaysclinicalbenefitinimprovingsymptomsofpostmenopausalsyndrome.Inmales,quinestroldecreasestheweightofthetestis,epididymis,seminalvesicle,andprostate,decreasesspermcount,anddecreaseslevelsoftestosterone,lutropin,andfollitropin.Infemales,quinestroldecreaseslevelsoffollicle-stimulatinghormone(FSH)andluteinizinghormone(LH),increaseslevelsofprogesteroneandestrADIol,andaltersestrogenreceptorexpression.Quinestrolincreasesoxidativestressbydecreasingactivityofsuperoxidedismutase(SOD)andglutathioneperoxidaseandincreasinglevelsofNOandmalondialdehyde.Inotheranimalmodels,thiscompoundinhibitsinvestigativereproductivebehavior.

ProductInfo

CasNo.

152-43-2

Purity

≥98%

Formula

C25H32O2

FormulaWt.

364.52

IUPACName

(8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol

Synonym

Eston,Estrovis,Plestrovis

MeltingPoint

107-108°C

Appearance

Whiteorpracticallywhite,odorless

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

Q8135InfoSheetPDF

References

LiJ,WangH,ZhangJ,etal.Abnormalsecretionofreproductivehormonesandantioxidantstatusinvolvedinquinestrol-inducedreproductivetoxicityinadultmalerat.TissueCell.2013Oct1.pii:S0040-8166(13)00081-5.PMID:24183492.

LiuQ,QinJ,ChenQ,etal.FertilitycontrolofRattusnitidususingquinestrol:effectsonreproductiveorgansandsocialbehavior.IntegrZool.2013Apr;8Suppl1:9-17.PMID:23621467.

LvX,GuoY,ShiD.Effectsofquinestrolonreproductivehormoneexpression,secretion,andreceptorlevelsinfemaleMongoliangerbils(Merionesunguiculatus).Theriogenology.2012Apr1;77(6):1223-31.PMID:22284225.

JaschevatzkyOE,AndermanS,ShalitA,etal.Thetreatmentofpostmenopausalsyndromebymonthlyoraldosesofquinestrol.ActaObstetGynecolScand.1979;58(2):175-8.PMID:452871.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂