GentamycinisanaminoglycosideantibioticoriginallyproducedbyMicromonospora.Gentamycinbindstheribosomal30Ssubunit,preventingformationoftheinitiationcomplex,suppressingtranslocation,andinhibitingproteinsynthesis.Gentamycindisplaysantibacterialefficacyagainstsomegrampositivebacteriaandmanygramnegativebacteria.
| CasNo. | 1405-41-0 |
|---|---|
| Purity | ≥98% |
| FormulaWt. | 551.73 |
| IUPACName | 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuricacid |
| Synonym | GentamicinCcomplexsulfate;Alcomicin;Garamycin;Gentacin;Lugacin;Ophtagram;Pangram;Sulmycin |
| MeltingPoint | 218-237°C |
| Solubility | Solubleinethyleneglycolandformamide. |
| Appearance | White/AlmostWhitePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | G1658MSDSPDF |
|---|---|
| InfoSheet | G1658InfoSheetPDF |
CavalloG,MartinettoP.Themechanismofactionofaminoglycosides.GBatteriolVirolImmunol.1981Jul-Dec;74(7-12):335-46.PMID:6182050.
HahnFE,SarreSG.Mechanismofactionofgentamicin.JInfectDis.1969Apr-May;119(4):364-9.PMID:4892389.
