IkarugamycinisanantibioticinitiallyproducedbyspeciesofStreptomycesthatexhibitsantibacterial,anti-protozoal,andanticanceractivities.Ikarugamycinpreventsformationofthebacterial70Sribosomalsubunit,inhibitingproteintranslation.Invitro,ikarugamycininhibitsCCP-dependentphagocytosis,preventingPMA-induceddownregulationofCD4.Additionally,ikarugamycininhibitsuptakeofoxidizedLDL,preventingaccumulationofcholesterolesterinmacrophages.
| CasNo. | 36531-78-9 |
|---|---|
| Purity | ≥98% |
| Formula | C29H38N2O4 |
| FormulaWt. | 478.62 |
| Appearance | WhiteCrystalPowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | I4000MSDSPDF |
|---|---|
| InfoSheet | I4000InfoSheetPDF |
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