Imipenemisaβ-lactamcarbapenemantimicrobial.Imipenemexhibitsbroad-spectrumantibacterialactivityagainstbothgrampositiveandgramnegativebacteria;itisespeciallyactiveagainstPseudomonasaeruginosaaswellasspeciesofEnterococcus.Likeotherβ-lactamantibiotics,imipenempreventsbacterialcellwallsynthesisbyinhibitingpenicillinbindingproteins.
| CasNo. | 74431-23-5 |
|---|---|
| Purity | ≥98% |
| Formula | C12H17N3O4S•H2O |
| FormulaWt. | 317.36 |
| MeltingPoint | 106-111°C |
| Solubility | Water10mg/ml,methanol5mg/ml,ethanol0.2mg/ml |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | I4934MSDSPDF |
|---|---|
| InfoSheet | I4934InfoSheetPDF |
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ClissoldSP,ToddPA,Campoli-RichardsDM.Imipenem/cilastatin.Areviewofitsantibacterialactivity,pharmacokineticpropertiesandtherapeuticefficacy.Drugs.1987Mar;33(3):183-241.PMID:3552595.
