Imipenem is a β-lactam carbapenem antimicrobial. Imipenem exhibits broad-spectrum antibacterial activity against both gram positive and gram negative bacteria; it is especially active against Pseudomonas aeruginosa as well as species of Enterococcus. Like other β-lactam antibiotics, imipenem prevents bacterial cell wall synthesis by inhibiting penicillin binding proteins.
| Cas No. | 74431-23-5 |
|---|---|
| Purity | ≥98% |
| Formula | C12H17N3O4S • H2O |
| Formula Wt. | 317.36 |
| Melting Point | 106-111°C |
| Solubility | Water 10 mg/ml, methanol 5 mg/ml, ethanol 0.2 mg/ml |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | I4934 MSDS PDF |
|---|---|
| Info Sheet | I4934 Info Sheet PDF |
El-Gamal MI, Oh CH. Current status of carbapenem antibiotics. Curr Top Med Chem. 2010;10(18):1882-97. PMID: 20615191.
Clissold SP, Todd PA, Campoli-Richards DM. Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. Drugs. 1987 Mar;33(3):183-241. PMID: 3552595.
